NIH-funded research U01 cooperative agreement

Cincinnati Children's Food Allergy Clinical Center

Official title: Consortium of Food Allergy Research Clinical Research Center at Cincinnati Children's Hospital Medical Center (CoFAR-CRC:CCHMC)

Funded at Cincinnati Childrens Hosp Med Ctr · NIH-11321529 · Data updated 2026-11-12

This center connects children and adults with food allergies (including IgE-mediated allergies, eosinophilic esophagitis, and FPIES) to specialized care, clinical studies, and biobanking at Cincinnati Children's Hospital.

More Allergy research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionCincinnati Childrens Hosp Med Ctr
NIH-funded
Lab location1 site (Cincinnati, United States)
Project startMarch 1, 2024
Project endFebruary 28, 2031
Funding year2026
Award (this year)$380,000
NIH project number5U01AI181966-03
Project IDNIH-11321529 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are children and adults with suspected or confirmed food allergies, including IgE-mediated food allergy, eosinophilic esophagitis (EoE), and food protein–induced enterocolitis syndrome (FPIES), with particular interest in infants and underserved populations.

Less likely to help

People without food-allergy conditions or those seeking only immediate clinical treatment rather than research participation may not directly benefit from this center's studies.

What this research studies

You can join a center that brings together clinics, research teams, and a registry to study different types of food allergy across ages. The team collects medical data and biological samples for a biobank and uses those resources to run clinical trials and lab studies that aim to improve care. The center focuses on recruiting diverse populations, including infants, adults, and underrepresented groups, and supports coordinated, multi-site trials. Participation may include clinic visits, sample donation, and follow-up through the CoFAR network.

Why it matters

Potential benefit: If successful, the center could increase access to clinical trials, generate better tests and treatments for food allergies, and improve long-term care for affected patients.

How similar studies have gone: CoFAR and affiliated clinical research centers have a track record of initiating and successfully running multi-center food allergy trials and building registries and biobanks.

Where this research is happening

  • Cincinnati Childrens Hosp Med Ctr
    Cincinnati, United States
    Active

Researchers

  • Principal investigator: Assa'ad, Amal Halim — Cincinnati Childrens Hosp Med Ctr
  • Study coordinator: Assa'ad, Amal Halim

Related research

Other NIH-funded projects on the same topics.

  • New Horizons in preventing and treating food allergy

    A Johns Hopkins-led effort aims to advance how we prevent and treat food allergies across all ages by coordinating high-quality studies and developing better therapies.

    NIH research Johns Hopkins University · Baltimore, United States · NIH-11600582

  • New Horizons in Food Allergy Prevention and Treatment

    A large, multi-site program at Johns Hopkins aims to advance prevention and treatment of food allergies across all ages.

    NIH research Johns Hopkins University · Baltimore, United States · NIH-11580809

  • Food allergy outcomes by race/ethnicity from infancy through adolescence

    This study follows children with food allergies over time to understand how race and ethnicity relate to allergy management, outcomes, and quality of life.

    NIH research Northwestern University · Chicago, United States · NIH-11579222

  • Gut-brain links in food allergy responses

    A research grant is exploring how signals between the gut and brain drive dangerous reactions to foods, with the goal of helping people with food allergies.

    NIH research Yale University · New Haven, United States · NIH-11551492

  • Targeting gut microbes to restore food-tolerance in adults

    Aims to understand how gut bacteria and the lining of the gut interact to keep people with food allergies tolerant to what they eat.

    NIH research Boston Children's Hospital · Boston, United States · NIH-11551491

  • Environment and early-life exposures shaping food allergy in children

    This grant looks at how a child’s first year and their home environment may influence whether they develop food allergies, focusing on indoor exposures and microbes.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11450430

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.