Chronic kidney disease in children and young adults

Chronic Kidney Disease in Children (CKiD V)

NIH-funded research Children's Mercy Hosp (Kansas City, Mo) · NIH-11379173

Following children and teens with chronic kidney disease over time to track how their kidney function and heart health change and what factors speed decline.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionChildren's Mercy Hosp (Kansas City, Mo) NIH-funded
Lab location1 site (Kansas City, United States)
Project IDNIH-11379173 on NIH RePORTER

What this research studies

If you join, the study will continue following children already enrolled and will invite 14- to 17-year-olds so researchers can watch changes as you grow into young adulthood. Blood pressure and lab tests can be done at home through national lab contractors and health records will be linked to fill in information between visits. You will be able to enter information online or by phone, and the team will combine clinical and social data to build tools that predict who may lose kidney function faster. The study will also look at how puberty and episodes of acute kidney injury affect long-term kidney and heart health.

Who could benefit from this research

Good fit: Children and teenagers with chronic kidney disease—especially those aged 14–17 or who are transitioning from pediatric to adult care—are the ideal candidates.

Not a fit: People without chronic kidney disease, or those seeking immediate therapeutic benefit rather than monitoring or research participation, are unlikely to receive direct medical benefit.

Why it matters

Potential benefit: Could help doctors predict who is at higher risk of faster kidney decline and guide earlier monitoring or treatments to protect kidneys and the heart.

How similar studies have performed: Earlier phases of the CKiD cohort and other long-term pediatric kidney studies have produced important findings, though combining machine-learning prediction with remote home testing is a newer approach.

Where this research is happening

Kansas City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.