Chronic kidney disease in children and young adults
Official title: Chronic Kidney Disease in Children (CKiD V)
Funded at Children's Mercy Hosp (Kansas City, Mo) · NIH-11379173 · Data updated 2026-11-12
Following children and teens with chronic kidney disease over time to track how their kidney function and heart health change and what factors speed decline.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Mercy Hosp (Kansas City, Mo) NIH-funded |
| Lab location | 1 site (Kansas City, United States) |
| Project start | September 30, 2003 |
| Project end | July 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $81,527 |
| NIH project number | 3U01DK066143-23S2 |
| Project ID | NIH-11379173 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children and teenagers with chronic kidney disease—especially those aged 14–17 or who are transitioning from pediatric to adult care—are the ideal candidates.
✕Less likely to help
People without chronic kidney disease, or those seeking immediate therapeutic benefit rather than monitoring or research participation, are unlikely to receive direct medical benefit.
What this research studies
If you join, the study will continue following children already enrolled and will invite 14- to 17-year-olds so researchers can watch changes as you grow into young adulthood. Blood pressure and lab tests can be done at home through national lab contractors and health records will be linked to fill in information between visits. You will be able to enter information online or by phone, and the team will combine clinical and social data to build tools that predict who may lose kidney function faster. The study will also look at how puberty and episodes of acute kidney injury affect long-term kidney and heart health.
Why it matters
Potential benefit: Could help doctors predict who is at higher risk of faster kidney decline and guide earlier monitoring or treatments to protect kidneys and the heart.
How similar studies have gone: Earlier phases of the CKiD cohort and other long-term pediatric kidney studies have produced important findings, though combining machine-learning prediction with remote home testing is a newer approach.
Where this research is happening
-
Children's Mercy Hosp (Kansas City, Mo)
Kansas City, United States Active
Researchers
- Principal investigator: Warady, Bradley Alan — Children's Mercy Hosp (Kansas City, Mo)
- Study coordinator: Warady, Bradley Alan
Related research
Other NIH-funded projects on the same topics.
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Personalized CKD-MBD care using systems biology and AI
A patient-facing program aims to tailor mineral-balance therapy for people with chronic kidney disease by using a computer model and smart decision rules to predict who will respond best to treatments.
-
Mitigating DKA in people with type 1 diabetes and kidney disease using SGLT1/2 inhibitors
This project tests a new way to prevent dangerous diabetic ketoacidosis in people with type 1 diabetes and chronic kidney disease who are using SGLT inhibitors, by tracking ketones in real time and combining glucose-keton data for safer therapy.
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Chronic Kidney Disease in Children: following young people as they grow up with CKD
A long-term study in kids with chronic kidney disease tracks kidney function and heart health as they transition into adulthood.
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Chronic Kidney Disease in Children follow-up study
A long-term study that follows kids with kidney disease as they grow into young adults, collecting health data from home and official records.
-
Malaria-related kidney injury and its link to chronic kidney disease in children
This grant looks at why some children who have malaria develop kidney injury and later chronic kidney disease, focusing on how severe malaria affects the kidneys over time.
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Boosting self-care and physical activity for older adults with chronic kidney disease
This program helps older adults with chronic kidney disease build the skills, confidence, and motivation to be more physically active.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.