Choosing and using HIV prevention (PrEP) that fits you

RFA-PS-21-003: PrEP Choice: Increasing the Use of HIV Pre-exposure Prophylaxis in an Era of Choices

['FUNDING_U01'] · FLORIDA STATE UNIVERSITY · NIH-11128323

This project tries ways to help people at risk for HIV pick the right PrEP option and stay on it to reduce their chance of getting HIV.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorFLORIDA STATE UNIVERSITY (nih funded)
Locations1 site (TALLAHASSEE, UNITED STATES)
Trial IDNIH-11128323 on ClinicalTrials.gov

What this research studies

You would be offered clear information and choices about PrEP — such as daily pills or newer long-acting options — plus support to help you decide what fits your life. The research team will partner with clinics and community groups to provide counseling, decision tools, and navigation services. They will follow participants over time to see which approaches lead to more people starting and continuing PrEP. The aim is to identify straightforward, clinic-ready methods to help more people stay protected from HIV.

Who could benefit from this research

Good fit: Ideal participants are people at risk for HIV who are interested in prevention options — for example, those with recent condomless sex, partners with HIV, men who have sex with men, transgender people, or people who inject drugs.

Not a fit: People who are not at risk for HIV, already stably using an effective prevention method, or unable to attend clinic visits are less likely to benefit.

Why it matters

Potential benefit: If successful, more people at risk could start and keep using PrEP, lowering new HIV infections.

How similar studies have performed: Previous programs offering navigation, counseling, and outreach have increased PrEP starts, and long-acting injectable PrEP has shown efficacy, but real-world strategies for offering choice and sustaining use are still being refined.

Where this research is happening

TALLAHASSEE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.