Choline supplementation during pregnancy to reduce effects of alcohol on infant development
A Randomized, Double-Blind, Placebo-controlled Clinical Trial of Choline Supplementation during Pregnancy to Mitigate Adverse Effects of Prenatal Alcohol Exposure on Growth and Cognitive Development
This study is looking at whether taking choline during pregnancy can help protect babies from the negative effects of alcohol exposure, and it's for pregnant women who drink alcohol.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wayne State University NIH-funded |
| Lab location | 1 site (Detroit, United States) |
| Project ID | NIH-10836407 on NIH RePORTER |
What this research studies
This research investigates whether choline supplementation during pregnancy can help mitigate the adverse effects of prenatal alcohol exposure on infant growth and cognitive development. Pregnant women who consume alcohol will be randomly assigned to receive either choline or a placebo, allowing researchers to compare the outcomes for their infants. The study aims to build on previous animal studies that suggested choline may protect against developmental issues caused by alcohol. By focusing on a community with high rates of alcohol consumption during pregnancy, the research seeks to provide valuable insights into effective nutritional interventions.
Who could benefit from this research
Good fit: Ideal candidates for participation are pregnant women who consume alcohol and are seeking ways to support their infants' development.
Not a fit: Patients who do not consume alcohol during pregnancy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved growth and cognitive outcomes for infants exposed to alcohol in utero.
How similar studies have performed: Previous animal studies have shown promising results, but human studies have been inconsistent, making this research both relevant and necessary.
Where this research is happening
Detroit, United States
- Wayne State University — Detroit, United States (Active)
Researchers
- Principal investigator: Jacobson, Sandra W. — Wayne State University
- Study coordinator: Jacobson, Sandra W.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.