Children's HIV data and analysis center
Core-001
['FUNDING_P01'] · EMORY UNIVERSITY · NIH-11312674
This project combines detailed blood and tissue data from children living with HIV to find immune patterns that help the virus persist.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | EMORY UNIVERSITY (nih funded) |
| Locations | 1 site (ATLANTA, UNITED STATES) |
| Trial ID | NIH-11312674 on ClinicalTrials.gov |
What this research studies
This program brings together teams who analyze blood and tissue samples from infants, children, and teens living with HIV using high-resolution single-cell and other 'omics' technologies. A dedicated bioinformatics core will manage samples, track data with a lab information system, and run standardized analysis pipelines. The core will combine multiple types of molecular data to build network models that show how immune and metabolic pathways support the viral reservoir in children. Those models are intended to point to targets for future therapies aimed at clearing HIV in young people.
Who could benefit from this research
Good fit: Ideal candidates are infants, children, and adolescents living with HIV who can provide blood or tissue samples for research through participating clinical sites.
Not a fit: People without HIV, or children whose samples are not collected or who cannot give consent, would not directly benefit from this specific core project.
Why it matters
Potential benefit: If successful, this work could reveal immune or metabolic targets that lead to new curative approaches for children living with HIV.
How similar studies have performed: Related single-cell and multiomic methods have yielded new insights in adult HIV and other diseases, but applying them specifically to pediatric HIV reservoirs is relatively new.
Where this research is happening
ATLANTA, UNITED STATES
- EMORY UNIVERSITY — ATLANTA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHARMA, ASHISH ARUNKUMAR — EMORY UNIVERSITY
- Study coordinator: SHARMA, ASHISH ARUNKUMAR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus