Childhood Health: Understanding Early Risks for Obesity and Mental Well-being

Retaining the CANDLE cohort to advance ECHO Cohort solution-oriented research and identify early-life modifiable risk factors for obesity and mental health problems in children

NIH-funded research University of Tennessee Health Sci Ctr · NIH-11319133

This project aims to understand how early life experiences influence a child's risk for developing obesity and mental health challenges.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Tennessee Health Sci Ctr NIH-funded
Lab location1 site (Memphis, United States)
Project IDNIH-11319133 on NIH RePORTER

What this research studies

We are looking at information from children and mothers already participating in the CANDLE and ECHO Cohorts to find early life factors that predict adolescent depression and obesity. Our goal is to pinpoint the most important factors so we can develop better ways to prevent these conditions. We are also exploring how a mother's stress during her own childhood and pregnancy might affect her child's mental health risk, and if family or community support can help buffer these effects. Additionally, we are developing a new way to measure a child's overall risk for mental health issues.

Who could benefit from this research

Good fit: This project uses existing data from children and mothers who are already part of the CANDLE and ECHO Cohorts.

Not a fit: Patients not already part of the CANDLE or ECHO Cohorts would not directly participate in this specific data analysis project.

Why it matters

Potential benefit: If successful, this work could lead to new ways to prevent obesity and mental health problems in children by identifying key factors that can be changed early in life.

How similar studies have performed: While individual risk factors have been studied, this project uses a large national dataset to systematically identify and prioritize the most powerful early life predictors, which is a novel approach for comprehensive prevention targets.

Where this research is happening

Memphis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.