Childhood growth, home environment, and stress (PROGRESS) cohort

The Programming Research in Obesity, GRowth, Environment and Social Stress (PROGRESS) Cohort

NIH-funded research Icahn School of Medicine at Mount Sinai · NIH-11516986

This project follows children from pregnancy through adolescence to learn how home air pollution, metals, and social stress affect growth, breathing, and brain development.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionIcahn School of Medicine at Mount Sinai NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11516986 on NIH RePORTER

What this research studies

If you join PROGRESS, researchers will follow you from pregnancy into childhood and adolescence and collect home environmental samples, biological samples, and surveys about family life and stress. They use new methods like bioethnographies (detailed observations of daily life), passive samplers, and environmental sensors to measure air pollution and metal exposures in homes. The team also conducts standardized tests of thinking, lung function, and metabolism to link exposures with growth, asthma, and neurodevelopment. Data are shared with other child health groups to speed discoveries and guide ways to reduce harmful home exposures.

Who could benefit from this research

Good fit: Pregnant people and their children (from birth through adolescence) living near the partner study sites, especially in homes with potential air pollution or other environmental exposures, are the ideal candidates.

Not a fit: People who are not pregnant, not the child of an enrolled participant, or whose health issues are unrelated to home environmental or social exposures are unlikely to receive direct benefit from participation.

Why it matters

Potential benefit: If successful, this work could reveal specific home exposures that raise the risk of asthma, growth problems, or learning delays and point to ways families and communities can lower those risks.

How similar studies have performed: Other birth cohort studies have linked early-life pollution and metals to child health, and this project builds on that evidence while adding novel home-based sampling and ethnographic methods.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.