Chest and belly breathing coordination in Parkinson's disease

Ribcage-abdominal movement asynchrony in persons with Parkinsons disease

NIH-funded research Medical University of South Carolina · NIH-11161575

We are measuring how the chest and belly move together during breathing in people with Parkinson's disease to better understand voice and breathing problems.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina NIH-funded
Lab location1 site (Charleston, United States)
Project IDNIH-11161575 on NIH RePORTER

What this research studies

We are combining breathing recordings from five past human studies to look at how the ribcage and abdomen move in people with Parkinson's disease. The team will analyze timing and coordination between chest and belly motion to identify patterns of asynchrony that could reduce speaking volume or increase the work of breathing. Because the project uses existing human-subject datasets, no new procedures are required from patients, but the results could point to measurable targets for therapy. Findings will be linked to common symptoms like hypophonia and breathlessness to help refine voice and respiratory care approaches.

Who could benefit from this research

Good fit: Adults with Parkinson's disease who experience reduced speaking volume or breathing difficulty are the main group relevant to these findings, though the project uses existing data rather than enrolling new participants.

Not a fit: People without Parkinson's disease or those with normal breathing and voice function are unlikely to gain direct benefit from this analysis.

Why it matters

Potential benefit: If successful, this work could help clinicians tailor voice and breathing therapies to specific chest–abdomen timing problems in Parkinson's disease.

How similar studies have performed: Prior studies have shown reduced speaking volume and some respiratory changes in Parkinson's, but direct analysis of chest–abdomen timing in PD is limited, so this approach is relatively novel.

Where this research is happening

Charleston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Amyotrophic Lateral Sclerosis Motor Neuron DiseaseBlood Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.