Chatbot-based mental health app for middle-aged and older adults with depression or anxiety and chronic pain

Digital mental health intervention for middle-aged and older adults with depression and/or anxiety and coexisting chronic pain

NIH-funded research Washington University · NIH-11258556

This project tests a chatbot and coach-based app adapted to help middle-aged and older adults who have depression or anxiety alongside chronic pain.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11258556 on NIH RePORTER

What this research studies

This project partners with Wysa and Washington University to adapt a mental health app so it fits the needs of middle-aged and older adults who also live with chronic pain. The app combines chatbot-delivered cognitive behavioral tools, mindfulness, behavioral activation, pain acceptance strategies, and sleep support with optional human coaching. Researchers will refine the app’s design for older users and follow participants using the app to track mood, pain coping, and sleep over time. Participation will likely include using the app, giving feedback, and sharing symptom and usage information.

Who could benefit from this research

Good fit: Ideal candidates are middle-aged or older adults who have depression and/or anxiety together with chronic pain and are willing to use a smartphone app or digital tools.

Not a fit: People who do not have chronic pain, who are unable or unwilling to use smartphone apps, or who need urgent psychiatric or pain intervention may not benefit from this app-based approach.

Why it matters

Potential benefit: If successful, the adapted app could make it easier for middle-aged and older adults with chronic pain to access helpful mental health and pain-coping tools and reduce depression and anxiety symptoms.

How similar studies have performed: Digital mental health apps have reduced depression and anxiety in many populations, but versions specifically tailored for older adults with coexisting chronic pain are relatively new and less tested.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.