NIH-funded research R21 grant

Characterization and Rehabilitation of Jaw Movement with a Wearable 4-DOF Robotic Exoskeleton

Official title: Characterization and Rehabilitation of Mandibular Functions Using Novel Wearable Robotics

Funded at Columbia Univ New York Morningside · NIH-11445531 · Data updated 2026-11-12

A wearable robotic jaw exoskeleton will measure jaw motion and provide guided, multi-directional jaw forces to help people recovering from trismus.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionColumbia Univ New York Morningside
NIH-funded
Lab location1 site (New York, United States)
Project startSeptember 11, 2026
Project endAugust 31, 2028
Funding year2026
Award (this year)$439,707
NIH project number1R21DE036374-01
Project IDNIH-11445531 on NIH RePORTER

Who could benefit from this research

Could help

Patients experiencing trismus after cancer treatment who are candidates for jaw rehabilitation.

Less likely to help

Patients without jaw mobility impairment or those unable to participate in wearable robotics rehabilitation may not benefit.

What this research studies

This project designs a 4-DOF robotic jaw exoskeleton that can track jaw movement and apply controlled forces to retrain jaw motion during cancer treatment recovery. The device will collect data on jaw kinematics to guide personalized rehab plans and quantify progress. Researchers aim to compare this active, data-driven approach with current passive rehabilitation methods to see if recovery can be accelerated. The work combines biomechanics, robotics, and clinical observation to support clinicians in tailoring therapy for each patient. The long-term vision is a data-informed rehabilitation toolkit for patients affected by jaw mobility limitations after cancer treatment.

Why it matters

Potential benefit: If successful, patients could regain jaw function faster and more fully, improving eating, speaking, and quality of life.

How similar studies have gone: Prior approaches are mostly passive; this study’s integrated, data-driven device is a novel shift with potential for meaningful improvement.

Where this research is happening

  • Columbia Univ New York Morningside
    New York, United States
    Active

Researchers

  • Principal investigator: Agrawal, Sunil K. — Columbia Univ New York Morningside
  • Study coordinator: Agrawal, Sunil K.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.