Chagas disease diagnosis and care in São Paulo–Minas Gerais (SaMiTrop)
"Sao Paulo-Minas Gerais Center for Chagas Disease Treatment (SaMiTrop)"
['FUNDING_U01'] · FUNDACAO FACULDADE DE MEDICINA · NIH-11320749
This project brings better testing, follow-up, and access to treatment for people with Chagas disease in parts of Brazil.
Quick facts
| Phase | ['FUNDING_U01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | FUNDACAO FACULDADE DE MEDICINA (nih funded) |
| Locations | 1 site (SAO PAULO, BRAZIL) |
| Trial ID | NIH-11320749 on ClinicalTrials.gov |
What this research studies
If you take part, you would be connected with local primary-care teams who have followed people with Chagas disease for years and could get regular testing and follow-up. The project uses blood tests, antibody and biomarker measurements, and computer tools (including AI) to find more people who have the infection and to track how they respond to treatment such as benznidazole. Researchers build on long-term patient cohorts and active follow-up to test practical ways to increase diagnosis and link people to care. Visits and sample collection are done through local clinics in São Paulo and northern Minas Gerais.
Who could benefit from this research
Good fit: Ideal candidates are people living in endemic areas of northern Minas Gerais or São Paulo who have or may have Chagas disease, including those with cardiac symptoms or prior positive tests.
Not a fit: People who do not live in the study regions, those without Trypanosoma cruzi infection, or those with advanced cardiac disease unlikely to benefit from antiparasitic treatment may not receive direct benefit.
Why it matters
Potential benefit: If successful, this work could help many more people get diagnosed, receive antiparasitic treatment, and get better ongoing heart care.
How similar studies have performed: Previous SaMi-Trop projects have successfully followed large patient groups for over a decade and provided important data on disease progression and antibody trends, though a reliable cure-monitoring test is still lacking.
Where this research is happening
SAO PAULO, BRAZIL
- FUNDACAO FACULDADE DE MEDICINA — SAO PAULO, BRAZIL (ACTIVE)
Researchers
- Principal investigator: SABINO, ESTER CERDEIRA — FUNDACAO FACULDADE DE MEDICINA
- Study coordinator: SABINO, ESTER CERDEIRA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Cardiac Diseases, Cardiac Disorders