Cervical cancer vaccines and prevention program
SPORE in Cervical Cancer
This program develops new vaccines and better screening to protect and treat women and people with cervixes against HPV infection, precancer, and cervical cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11191594 on NIH RePORTER |
What this research studies
If you are someone at risk for or living with HPV-related cervical disease, this program aims to reach and protect the next generation through improved vaccination and screening. It supports four vaccine projects that build on successful preventive HPV vaccines and on new knowledge about immune responses and viral clearance. Some projects focus on therapeutic vaccines to help clear persistent HPV or treat precancer and cancer, while others improve HPV testing and genotyping to find infections earlier. The program also pays attention to people living with HIV and underserved groups, combining lab work, clinical trials, and screening programs.
Who could benefit from this research
Good fit: Ideal candidates include women and other people with cervixes who are at risk for HPV, have persistent HPV infection, cervical precancer (CIN), or cervical cancer, and people living with HIV for whom tailored approaches are being developed.
Not a fit: People without HPV-related conditions or whose health concerns are unrelated to cervical disease are unlikely to benefit from this program.
Why it matters
Potential benefit: Could lower the number of HPV infections and cervical cancers and offer better vaccine-based treatments for people with persistent HPV or precancerous lesions.
How similar studies have performed: Preventive HPV vaccines have been highly successful at stopping new infections, but therapeutic vaccines for treating established HPV disease are still experimental and an active area of research.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Wu, Tzyy-Choou — Johns Hopkins University
- Study coordinator: Wu, Tzyy-Choou
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.