Cervical cancer prevention in Rwanda for women living with HIV

Rwanda CASCADE Clinical Trials Site for cervical cancer prevention

NIH-funded research Research for Development · NIH-11190858

This project tries new ways to find high-risk HPV early and provide same-day care to women living with HIV in Rwanda.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionResearch for Development NIH-funded
Lab location1 site (Kigali, Rwanda)
Project IDNIH-11190858 on NIH RePORTER

What this research studies

If you join, you may be offered HPV screening with a cervical sample and, when needed, a quick visual exam and same-day treatment such as thermal ablation. The program works through Rwanda Biomedical Center clinics and combines clinic-based care, community outreach, and strengthened local lab and pathology services. The team has enrolled thousands of women before and will include follow-up visits to check healing and monitor for HPV or cervical changes. Participation helps build local capacity so care and results can be delivered more reliably over time.

Who could benefit from this research

Good fit: Women living with HIV in Rwanda who are eligible for cervical screening at participating clinics are the ideal candidates.

Not a fit: People who do not have a cervix, live outside Rwanda, or are not eligible for cervical screening are unlikely to benefit directly from this program.

Why it matters

Potential benefit: If successful, this could catch and treat precancerous changes earlier and lower cervical cancer rates and deaths among women with HIV.

How similar studies have performed: Similar programs using primary HPV testing with visual inspection and immediate treatment have shown success in low-resource settings, and this team has prior successful work in Rwanda.

Where this research is happening

Kigali, Rwanda

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.