Centralized bioinformatics resource for food allergy analysis
Official title: Bioinformatics Core
Funded at Food Allergy Science Initiative, INC. · NIH-11088821 · Data updated 2026-11-12
This study is working on a new resource to help scientists better understand food allergies by providing tools and support for analyzing important data about how different cells in our bodies react to food, making it easier for researchers to learn more about what causes these allergies.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Food Allergy Science Initiative, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project start | May 14, 2024 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $157,882 |
| NIH project number | 5P01AI179273-02 |
| Project ID | NIH-11088821 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with food allergies who may contribute to or benefit from advanced data analysis related to their condition.
✕Less likely to help
Patients without food allergies or those not involved in related research may not receive any benefit from this initiative.
What this research studies
This research focuses on creating a centralized bioinformatics core that will support the analysis of data related to food allergies. It will provide tools and expertise for analyzing gene expression from various cell types involved in food allergies, including gut epithelial, neuronal, and immune cells. The core will also develop user-friendly interfaces for researchers to access and interpret this data effectively. By optimizing data analysis pipelines and collaborating with other researchers, this initiative aims to enhance understanding of food allergies and their underlying mechanisms.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of food allergies, potentially benefiting patients through better diagnostic and therapeutic strategies.
How similar studies have gone: Previous research has shown success in utilizing bioinformatics approaches to analyze complex biological data, indicating that this method is promising and not entirely novel.
Where this research is happening
-
Food Allergy Science Initiative, INC.
Cambridge, United States Active
Researchers
- Principal investigator: Carroll, Thomas S — Food Allergy Science Initiative, INC.
- Study coordinator: Carroll, Thomas S
Related research
Other NIH-funded projects on the same topics.
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How gut nerves and immune cells interact in food allergy
This project looks at how contacts between gut nerves, immune cells, and hormone-producing gut cells affect allergic reactions to food for people with food allergies.
-
How mast cells trigger gut lining and nerve responses in food allergy
This project looks at how immune cells called mast cells change the gut lining and nerves in people with food allergies.
-
How nerves and the immune system cause food allergy symptoms
This project explores how nerves and the immune system cause the symptoms people with food allergies feel, like nausea, breathing changes, and low blood pressure.
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Food allergy data hub
A centralized team will build online tools to analyze genetic and imaging data to help researchers studying food allergies and the people they treat.
-
Custom genetically engineered mice for food allergy
This program creates specially modified mice to help scientists better understand and develop treatments for food allergies.
-
How the nerves and immune system affect food allergies
Researchers are looking at how the nervous system and immune system interact in people with food allergies to find better ways to prevent and treat reactions.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.