Central data hub for obstructive sleep apnea
Data Integration Core
This project combines health records, CPAP device data, genetics, and blood markers to improve prevention, diagnosis, and personalized care for people with obstructive sleep apnea.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-11184374 on NIH RePORTER |
What this research studies
You may be asked to allow researchers to link your medical record, CPAP usage data, and genetic or blood test results into a secure database. The Data Integration Core collects, cleans, and standardizes these different types of information so study teams can analyze them together. That combined information will help researchers predict who may develop OSA, find ways to prevent complications, and tailor treatments to each person's needs. The core is led by experts at the University of Pennsylvania who handle data privacy, storage, and analytic support for the program.
Who could benefit from this research
Good fit: Ideal participants are adults with diagnosed or suspected obstructive sleep apnea, people using CPAP, or those willing to share medical records and provide blood or genetic samples.
Not a fit: People without sleep apnea or those unwilling to share their medical records, CPAP device data, or biological samples are unlikely to benefit directly from this project.
Why it matters
Potential benefit: If successful, this work could help doctors spot OSA earlier and match patients with the treatments most likely to work for them.
How similar studies have performed: Other research combining medical records and device data in sleep medicine has shown promise, but integrating EHR, CPAP adherence, genetics, and biomarkers together at this scale is relatively new.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Holmes, John H. — University of Pennsylvania
- Study coordinator: Holmes, John H.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.