Central coordination of data and biosamples for lung transplant patients
Official title: Lung Transplant Consortium - Data Coordinating Center
Funded at Duke University · NIH-11161562 · Data updated 2026-11-12
This project will collect health information and blood/tissue samples from people who get lung transplants to help doctors learn how to prevent complications and improve long-term outcomes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | August 5, 2022 |
| Project end | July 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $2,270,471 |
| NIH project number | 5U24HL163122-04 |
| Project ID | NIH-11161562 on NIH RePORTER |
Who could benefit from this research
✓Could help
People who are receiving or have recently received a lung transplant at one of the participating transplant centers are the ideal candidates for participation.
✕Less likely to help
People who do not have a lung transplant or who cannot access a participating center are unlikely to be eligible or directly benefit from joining.
What this research studies
If you join, teams at many hospitals will follow you before and after your lung transplant, recording medical details and taking regular blood and other samples. A single Data Coordinating Center will run the common protocol so data and samples are collected the same way across sites. The effort aims to enroll about 3,200 lung transplant patients and store clinical data and serial biospecimens for future research. Duke University and the University of Pennsylvania will manage the operations and the biorepository to support studies that use these resources.
Why it matters
Potential benefit: If successful, this resource could help doctors reduce early complications and improve long-term survival after lung transplant.
How similar studies have gone: Previous multicenter transplant registries and observational studies have provided useful insights into transplant outcomes, and this builds on those established approaches.
Where this research is happening
-
Duke University
Durham, United States Active
Researchers
- Principal investigator: Palmer, Scott M — Duke University
- Study coordinator: Palmer, Scott M
Related research
Other NIH-funded projects on the same topics.
-
Exercise-based frailty program for people awaiting lung transplants
A tailored exercise and lifestyle program is being tested to reduce frailty and improve outcomes for people waiting for a lung transplant.
-
Understanding why a lung transplant sometimes fails early and how to tailor treatment
A study of people receiving lung transplants to find molecular differences that cause early graft failure and point to better, personalized therapies.
-
Targeting inflammation and alloimmunity in lung transplant recipients with clazakizumab
A study to see if blocking IL-6 with clazakizumab can improve survival and reduce rejection in people who have received a lung transplant.
-
Vaccination responses in lung transplant patients
This grant studies how people who have received lung transplants respond to COVID-19 vaccines and why their antibody responses may be limited.
-
The Post-Lung Transplant Aging in Immune Cells in Donor Lungs
This grant explores how aging donor lungs affect lung transplant outcomes by studying immune cells called alveolar macrophages.
-
Predictors of Lung Transplant Success and Costs
This study looks at what pre-transplant patient factors and biology predict a smooth recovery and lower costs after lung transplant.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.