Center to map and share data on aging (senescent) cells
Cellular Senescence Network (SenNet) Consortium Organization and Data Coordinating Center (CODCC)
This project creates a national hub that collects and shares data about aging (senescent) cells to help researchers working on cancer and age-related conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project ID | NIH-11191497 on NIH RePORTER |
What this research studies
This center brings together teams that collect human tissue and blood samples, standardize lab tests, and organize single-cell data about senescent cells. It coordinates tissue centers, technology developers, and data platforms so scientists can compare results and build shared atlases. The focus is on human-relevant samples across normal, experimental, and disease conditions including cancer and aging-affected organs. By making methods and datasets widely available, the center aims to speed research into how senescent cells affect health.
Who could benefit from this research
Good fit: People with cancer, age-related conditions, or those willing to donate tissue or blood samples for research would be most relevant to this work.
Not a fit: This grant funds coordination and data sharing rather than a clinical treatment, so people seeking direct therapeutic benefit are unlikely to gain immediate personal benefit.
Why it matters
Potential benefit: If successful, the effort could speed discoveries that lead to better detection and treatments for diseases linked to senescent cells, such as some cancers and age-related decline.
How similar studies have performed: Other large-scale cell-mapping consortia have successfully produced shared atlases and data platforms, but applying these approaches specifically to senescent cells is newer and less tested.
Where this research is happening
Pittsburgh, United States
- University of Pittsburgh at Pittsburgh — Pittsburgh, United States (Active)
Researchers
- Principal investigator: Silverstein, Jonathan C. — University of Pittsburgh at Pittsburgh
- Study coordinator: Silverstein, Jonathan C.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.