Center on Stress, Trauma, and Resilience

COBRE for Stress, Trauma and Resilience (STAR)

NIH-funded research Miriam Hospital · NIH-11178488

This center looks at how early-life stress and trauma affect physical and mental health and aims to find ways to help pregnant people, children, young adults, and adults affected by early trauma.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMiriam Hospital NIH-funded
Lab location1 site (Providence, United States)
Project IDNIH-11178488 on NIH RePORTER

What this research studies

Researchers at The Miriam Hospital are building a center that brings together multiple projects and junior investigators to study how stress and trauma from pregnancy through childhood and young adulthood influence health. The work combines real-time ecological sampling (asking about experiences and symptoms in daily life) with biological measures to identify short-term mechanisms of risk and resilience. The center supports pilot studies and mentorship to move quickly from discovery to practical targets for interventions. If eligible, people may be invited to provide survey data, wear sensors, give biospecimens, or take part in small pilot intervention studies.

Who could benefit from this research

Good fit: Ideal participants are pregnant people, children (including ages 0–11), young adults, or adults with a history of early-life adversity or trauma who can take part in observational or pilot intervention studies.

Not a fit: People without a history of early-life stress or those seeking immediate clinical treatment rather than research participation are unlikely to gain direct benefit from this center's projects.

Why it matters

Potential benefit: If successful, this work could point to new early-life screening tools or intervention targets to prevent or reduce long-term mental and physical health problems after childhood trauma.

How similar studies have performed: Previous research has linked childhood adversity to later health problems and some intervention approaches show promise, but combining ecological momentary sampling with biological markers in a coordinated center is relatively novel.

Where this research is happening

Providence, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.