NIH-funded research NIH-funded research

Center for Integrative Research on Childhood Adversity (CIRCA) at OSU

Official title: Center for Integrative Research on Childhood Adversity

Funded at Osu Center for Health Sciences · NIH-11413501 · Data updated 2026-11-12

A center-led effort to study how adverse childhood experiences affect brain, body, and behavior, with the goal of preventing and healing effects across development.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOsu Center for Health Sciences
NIH-funded
Lab location1 site (Tulsa, United States)
Project startAugust 1, 2016
Project endJune 30, 2027
Funding year2026
Award (this year)$1,922,128
NIH project number5P20GM109097-10
Project IDNIH-11413501 on NIH RePORTER

Who could benefit from this research

Could help

Children and adolescents who have experienced adverse childhood experiences and their families may benefit from future translational applications and interventions arising from this research.

Less likely to help

Some participants may not directly benefit, particularly if the study focuses on mechanisms or non-interventional aims rather than immediate therapies.

What this research studies

This program builds an interdisciplinary center at Oklahoma State University to study how childhood adversity affects nervous, hormonal, metabolic, and immune systems. It uses collaborative, team-based research to identify mechanisms and pathways that link early stress to later health outcomes and to explore prevention and recovery strategies. The initiative expands infrastructure, supports multiple projects, and aims to translate findings into real-world interventions for affected youths and families.

Why it matters

Potential benefit: If successful, this work could lead to better understanding of how ACEs shape health and more effective prevention and healing approaches for children and adolescents.

How similar studies have gone: Prior phases demonstrated capability to secure external funding and build infrastructure for translational research on adversity and resilience.

Where this research is happening

  • Osu Center for Health Sciences
    Tulsa, United States
    Active

Researchers

  • Principal investigator: Croff, Julie May — Osu Center for Health Sciences
  • Study coordinator: Croff, Julie May

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.