Cellular and genomic imaging support for gastric tissue
Core B: Translational, Cellular and Molecular Analysis
['FUNDING_P01'] · STANFORD UNIVERSITY · NIH-11179414
This project uses advanced cell imaging and genetic testing on stomach tissue from people with precancerous stomach conditions to map cellular and microbial changes.
Quick facts
| Phase | ['FUNDING_P01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STANFORD UNIVERSITY (nih funded) |
| Locations | 1 site (STANFORD, UNITED STATES) |
| Trial ID | NIH-11179414 on ClinicalTrials.gov |
What this research studies
If I participate, my biopsy or donated tissue would be tracked in a lab system and processed using standardized protocols so results are consistent. Labs will run tests like bulk RNA sequencing, single-cell genomics, spatial transcriptomics, targeted DNA sequencing, and confocal microscopy, and may grow organoids from my tissue. The core centralizes sample handling and primary data processing so multiple research teams can share results. The combined data aim to create a detailed map of the stomach microenvironment across precancerous conditions.
Who could benefit from this research
Good fit: Ideal candidates are people who have precancerous stomach conditions or are undergoing gastric biopsy and are willing to donate tissue or allow their samples to be used for molecular and imaging analyses.
Not a fit: People without gastric disease or those seeking immediate treatment are unlikely to receive direct clinical benefit from participating, since this core provides research data rather than a therapy.
Why it matters
Potential benefit: If successful, this work could help researchers identify changes in stomach tissue that lead to earlier detection or new targets for preventing stomach cancer.
How similar studies have performed: Technologies like RNA sequencing, single-cell analysis, and spatial transcriptomics have been successfully used to map tissue biology, though translating those maps into routine clinical care is still emerging.
Where this research is happening
STANFORD, UNITED STATES
- STANFORD UNIVERSITY — STANFORD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: AMIEVA, MANUEL R — STANFORD UNIVERSITY
- Study coordinator: AMIEVA, MANUEL R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.