CardioWatch: Predicting Heart Problems After Radiation Exposure

CardioWatch: An Omics-Based Prediction Assay for Cardiac Late Effects ofAcute Radiation

['FUNDING_SBIR_2'] · NELSON SCIENTIFIC LABS LLC · NIH-11249430

This project is creating a blood test to help predict if people exposed to radiation might develop heart problems later on.

Quick facts

Phase['FUNDING_SBIR_2']
Study typeNih_funding
SexAll
SponsorNELSON SCIENTIFIC LABS LLC (nih funded)
Locations1 site (POTOMAC, UNITED STATES)
Trial IDNIH-11249430 on ClinicalTrials.gov

What this research studies

Many people who survive radiation exposure, such as from a nuclear event or cancer treatment, can develop serious heart issues years later. Currently, it's hard to know who is at risk until symptoms appear, making treatment difficult. This project is developing a special blood test, called CardioWatch, that looks at many different biological markers. The goal is to identify those at high risk for heart problems early, even before they feel sick, so doctors can start preventative care sooner.

Who could benefit from this research

Good fit: Ideal candidates for this research would be individuals who have survived acute radiation exposure and are currently asymptomatic but at risk for delayed cardiac effects.

Not a fit: Patients who have not experienced acute radiation exposure or who already have symptomatic radiation-induced heart disease may not directly benefit from this predictive test.

Why it matters

Potential benefit: If successful, this test could allow doctors to identify individuals at risk for radiation-induced heart disease much earlier, enabling timely interventions to prevent or lessen severe cardiac complications.

How similar studies have performed: This project extends prior Phase I work on the CardioWatch biomarker assay, suggesting foundational success in initial development.

Where this research is happening

POTOMAC, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acute Radiation Syndrome

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.