NIH-funded research NIH-funded research

Cardiac effects of weathered microplastics on the heart

Official title: Cardiac Effects of Weathered Microplastics

Funded at Morgan State University · NIH-11424551 · Data updated 2026-11-12

This project looks at how weathered microplastics found in the environment might affect heart cells and heart function in adults.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMorgan State University
NIH-funded
Lab location1 site (Baltimore, United States)
Project startAugust 7, 2026
Project endJuly 31, 2030
Funding year2026
Award (this year)$142,399
NIH project number1R16ES038835-01
Project IDNIH-11424551 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable to patient participation in this stage; laboratory studies use human cell models.

Less likely to help

No direct patient participation; study done in lab settings.

What this research studies

Researchers will study weathered microplastics that people are actually exposed to and test their effects on human heart cells in the lab. They will compare these weathered particles to pristine particles to see how aging changes toxicity, focusing on heart cell contraction, calcium signaling, and electrical stability. The study builds on prior work with simple PS particles, but uses more realistic, weathered samples to better reflect human exposure. Findings could clarify whether environmental microplastics pose a greater risk to heart health than previously thought.

Why it matters

Potential benefit: If successful, results could inform risk assessments and guidelines to protect heart health from environmental pollutants.

How similar studies have gone: Past work with pristine particles showed effects on heart cell functions, but weathered particles are less understood and this study is a novel step.

Where this research is happening

  • Morgan State University
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Li, Yuejin — Morgan State University
  • Study coordinator: Li, Yuejin

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.