NIH-funded research Sbir 2 grant

Capecitabine in tough breast cancer with a wearable electric field device

Official title: CuRrEnT: Capecitabine in RCB2/3 with a wearable induced Electric field device in Triple Negative Breast Cancer

Funded at Embiosys INC. · NIH-11418087 · Data updated 2026-11-12

A new wearable, washable garment delivers a gentle electric field to help treat triple-negative breast cancer in patients who have already tried standard therapies.

More Breast Cancer research and trials

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionEmbiosys INC.
NIH-funded
Lab location1 site (North Andover, UNITED STATES)
Project startSeptember 17, 2025
Project endAugust 31, 2027
Funding year2026
Award (this year)$870,482
NIH project number5R44CA310518-02
Project IDNIH-11418087 on NIH RePORTER

Who could benefit from this research

Could help

Adults with TNBC who have relapsed or are at high risk of relapse after standard treatment and are eligible for capecitabine.

Less likely to help

Patients with TNBC who cannot tolerate chemotherapy or do not respond to capecitabine may not benefit from this approach.

What this research studies

This grant supports testing a wearable device that provides a non-invasive electric field therapy in combination with capecitabine for women with hard-to-treat triple-negative breast cancer. The study builds on preclinical evidence showing the device can target cancer cells while being safe and comfortable to wear. Patients would receive standard care along with the wearable therapy, with monitoring for response and any side effects. The goal is to improve disease control and extend time before progression when used alongside existing treatments.

Why it matters

Potential benefit: If successful, patients could experience better control of TNBC and longer periods without progression when the wearable electric field is used with chemotherapy.

How similar studies have gone: Preclinical results in mouse models showed that the electric field therapy reduced cancer activity when combined with chemotherapy, but human data are not yet available.

Where this research is happening

  • Embiosys INC.
    North Andover, United States
    Active

Researchers

  • Principal investigator: Barron, Christopher — Embiosys INC.
  • Study coordinator: Barron, Christopher

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.