Cannabis and Memory in Older Adults

Effects of cannabis on age-related cognitive decline and Alzheimers disease pathology

NIH-funded research University of Florida · NIH-11111453

This research looks at how cannabis use affects memory and brain health in older adults, especially concerning age-related memory changes and Alzheimer's disease.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Florida NIH-funded
Lab location1 site (Gainesville, United States)
Project IDNIH-11111453 on NIH RePORTER

What this research studies

Many older adults are using cannabis for various reasons, but we don't fully understand how it impacts their thinking and memory. While most past research on cannabis and memory focused on younger people, this project will explore how cannabis, when used in common ways like smoking or edibles, affects the aging brain. We want to see if cannabis might help or harm memory and if it plays a role in conditions like Alzheimer's disease. This work aims to fill a critical gap in our knowledge to better inform older adults about cannabis use.

Who could benefit from this research

Good fit: Older adults who use cannabis or are considering its use, and those concerned about age-related cognitive decline or Alzheimer's disease, are ideal candidates to follow this research.

Not a fit: Patients who are not older adults or who do not use cannabis may not directly benefit from the specific findings of this research.

Why it matters

Potential benefit: If successful, this research could provide clear guidance to older adults and their doctors about the risks and benefits of cannabis use for cognitive health and Alzheimer's disease.

How similar studies have performed: Research on cannabis and cognition in older adults is very limited, making this a novel area, though some preclinical studies suggest cannabinoids might affect age-related brain changes.

Where this research is happening

Gainesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.