Cannabis and immune changes in young Black men living with HIV

Cannabis Use and Proximal Immune Dysregulation (CUPID)

NIH-funded research University of Miami Coral Gables · NIH-11238903

Looks at whether cannabis use is linked to inflammation and early immune aging in young Black men with HIV.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Miami Coral Gables NIH-funded
Lab location1 site (Coral Gables, United States)
Project IDNIH-11238903 on NIH RePORTER

What this research studies

If you join, researchers will enroll young Black men who have sex with men living with HIV and ask about cannabis use and life stress. They will collect blood to measure inflammation markers and leukocyte telomere length and use biological tests (not only self-report) to detect recent cannabis exposure. The team will follow participants over time with repeated visits to see short-term immune changes related to cannabis and stress. The goal is to learn whether cannabis use is tied to less inflammation or slower immune aging in this group.

Who could benefit from this research

Good fit: Young Black men who have sex with men living with HIV, including adolescents and young adults who can attend clinic visits, are the ideal candidates.

Not a fit: People without HIV, women, non-Black individuals, older adults, or those who do not use cannabis are unlikely to benefit directly from this work.

Why it matters

Potential benefit: If successful, this could clarify whether cannabis affects inflammation or immune aging and help guide lifestyle or medical advice for young Black men with HIV.

How similar studies have performed: Previous studies have been mostly cross-sectional and relied on self-report, so results are limited and this longitudinal, biomarker-focused approach is relatively novel for young Black MSM with HIV.

Where this research is happening

Coral Gables, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.