NIH-funded research R01 grant

Can speaking both Spanish and English help protect thinking skills in older Hispanic adults with mild memory problems?

Official title: Prospective study of bilingualism and cognitive reserve in the aging brain of Hispano adults with MCI

Funded at Florida Atlantic University · NIH-11472077 · Data updated 2026-11-12

This project follows Hispanic older adults with amnestic mild cognitive impairment to see if people who use both Spanish and English show stronger brain resilience than Spanish-only speakers.

More Aging research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionFlorida Atlantic University
NIH-funded
Lab location1 site (Boca Raton, United States)
Project startFebruary 15, 2023
Project endJanuary 31, 2028
Funding year2026
Award (this year)$56,940
NIH project number3R01AG080468-04S1
Project IDNIH-11472077 on NIH RePORTER

Who could benefit from this research

Could help

Hispanic adults with amnestic mild cognitive impairment who speak Spanish and English or who are Spanish monolinguals and are willing to complete language questionnaires, cognitive testing, and brain scans are ideal candidates.

Less likely to help

People without mild cognitive impairment, non-Hispanic individuals, or those unable or unwilling to undergo in-person visits and brain imaging are unlikely to benefit directly from participating.

What this research studies

You would join a group of Hispanic adults with amnestic mild cognitive impairment and be followed over time with regular thinking tests, detailed language and cultural questionnaires, and brain imaging scans. Researchers will carefully measure how and when you use each language, alongside social and acculturation factors, to define bilingualism more precisely. The study uses multiple types of brain scans to look for signs of cognitive reserve that might relate to bilingual language use. The goal is to compare bilingual and monolingual participants within an ongoing Florida Alzheimer's research cohort.

Why it matters

Potential benefit: If successful, the work could identify whether bilingual language use helps delay worsening memory or dementia symptoms in Hispanic older adults and inform prevention strategies.

How similar studies have gone: Some earlier studies have suggested bilingualism may protect thinking skills but findings have been inconsistent, so this larger longitudinal study with detailed language measures and brain imaging aims to provide clearer evidence.

Where this research is happening

  • Florida Atlantic University
    Boca Raton, United States
    Active

Researchers

  • Principal investigator: Rosselli, Monica — Florida Atlantic University
  • Study coordinator: Rosselli, Monica

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.