Can speaking both Spanish and English help protect thinking skills in older Hispanic adults with mild memory problems?

Prospective study of bilingualism and cognitive reserve in the aging brain of Hispano adults with MCI

NIH-funded research Florida Atlantic University · NIH-11472077

This project follows Hispanic older adults with amnestic mild cognitive impairment to see if people who use both Spanish and English show stronger brain resilience than Spanish-only speakers.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionFlorida Atlantic University NIH-funded
Lab location1 site (Boca Raton, United States)
Project IDNIH-11472077 on NIH RePORTER

What this research studies

You would join a group of Hispanic adults with amnestic mild cognitive impairment and be followed over time with regular thinking tests, detailed language and cultural questionnaires, and brain imaging scans. Researchers will carefully measure how and when you use each language, alongside social and acculturation factors, to define bilingualism more precisely. The study uses multiple types of brain scans to look for signs of cognitive reserve that might relate to bilingual language use. The goal is to compare bilingual and monolingual participants within an ongoing Florida Alzheimer's research cohort.

Who could benefit from this research

Good fit: Hispanic adults with amnestic mild cognitive impairment who speak Spanish and English or who are Spanish monolinguals and are willing to complete language questionnaires, cognitive testing, and brain scans are ideal candidates.

Not a fit: People without mild cognitive impairment, non-Hispanic individuals, or those unable or unwilling to undergo in-person visits and brain imaging are unlikely to benefit directly from participating.

Why it matters

Potential benefit: If successful, the work could identify whether bilingual language use helps delay worsening memory or dementia symptoms in Hispanic older adults and inform prevention strategies.

How similar studies have performed: Some earlier studies have suggested bilingualism may protect thinking skills but findings have been inconsistent, so this larger longitudinal study with detailed language measures and brain imaging aims to provide clearer evidence.

Where this research is happening

Boca Raton, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.