Calypso — a web tool to help care teams find genetic causes over time
Calypso: a web software system supporting team-based, longitudinal genomic diagnostic care
This project builds an easy-to-use web platform so doctors, genetic counselors, and lab teams can work together to find genetic causes of complex or unexplained conditions, including newborns in the NICU.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Utah State Higher Education System--University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-11292887 on NIH RePORTER |
What this research studies
If you or your child has a complex or unexplained condition, this project creates a web platform that helps your treating doctor, geneticists, bioinformaticians, and counselors share findings and follow your case over months or years. The software stores genomic data, clinical notes, and changing symptoms so teams can re-check interpretations as new gene-disease links appear. It supports team communication, tracks evidence about genetic variants, and documents diagnostic decisions in one place. The aim is to make it easier for clinical teams to coordinate and to reduce delays in reaching a genetic diagnosis.
Who could benefit from this research
Good fit: People with unexplained, complex, or evolving medical conditions—especially patients seen in undiagnosed disease clinics or newborns in NICUs undergoing rapid genome sequencing—are the most likely candidates to benefit.
Not a fit: Patients with conditions that are clearly non-genetic, those not receiving genomic testing, or people treated at centers that do not use this platform are unlikely to benefit directly.
Why it matters
Potential benefit: If successful, this could help get genetic diagnoses sooner and keep your care team coordinated as your condition changes.
How similar studies have performed: Existing tools help lab experts interpret genomes, but a team-focused, long-term tracking platform like this is relatively new and not yet widely proven.
Where this research is happening
Salt Lake City, United States
- Utah State Higher Education System--University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Marth, Gabor T — Utah State Higher Education System--University of Utah
- Study coordinator: Marth, Gabor T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.