Caenorhabditis Intervention Testing Program at Oregon
Funded at University of Oregon · NIH-11380567 · Data updated 2026-11-12
A research program in Oregon tests safe compounds in aging worms to identify interventions that might help people age healthier.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Oregon NIH-funded |
| Lab location | 1 site (Eugene, United States) |
| Project start | August 15, 2013 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $590,910 |
| NIH project number | 5U01AG045829-13 |
| Project ID | NIH-11380567 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not applicable to a specific patient group; the study involves worm models to identify interventions that could translate to human aging research.
✕Less likely to help
Direct patient benefit is not guaranteed; the study uses worm models and may not translate to humans.
What this research studies
This project uses the nematode C. elegans to screen chemical compounds for their ability to extend healthy lifespan across diverse genetic variants. It involves coordinated work among three labs to test promising interventions and see if benefits hold up in different worm strains that model human genetic diversity. Findings could guide preclinical and clinical research aimed at promoting healthier aging in people. The focus is on aging-related decline and how certain treatments might delay onset of age-related diseases.
Why it matters
Potential benefit: If successful, the work could inform new strategies to promote healthy aging and delay age-related diseases in humans.
How similar studies have gone: Prior aging research in model organisms has often identified interventions with translatable potential, though translation to humans remains hopeful and contingent.
Where this research is happening
-
University of Oregon
Eugene, United States Active
Researchers
- Principal investigator: Phillips, Patrick C. — University of Oregon
- Study coordinator: Phillips, Patrick C.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.