Building a diverse Alzheimer's genetics resource
Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)
This project will gather genetic and health information from people of African and Hispanic ancestry to improve understanding of Alzheimer's risk in those communities.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-11125993 on NIH RePORTER |
What this research studies
You would be invited to join a large effort to help researchers understand Alzheimer's disease in underrepresented communities. Participants will provide health and family history, take brief cognitive or clinical assessments, and give a DNA sample (usually blood or saliva). The team will use community-sensitive recruitment and retention approaches to address historical mistrust and make participation easier. Data from thousands of people of African and Hispanic ancestry will be combined and analyzed to find genetic risk factors missed by prior studies.
Who could benefit from this research
Good fit: Adults of African or Hispanic (Latino) ancestry, with or without Alzheimer's or related dementia, who are willing to provide health information and a DNA sample are ideal candidates.
Not a fit: People seeking immediate therapeutic benefit or those not of African or Hispanic ancestry are unlikely to receive direct clinical benefit from participating.
Why it matters
Potential benefit: If successful, this work could lead to more accurate genetic risk information and better-targeted prevention or treatments for people of African and Hispanic ancestry.
How similar studies have performed: Smaller genetics studies in European and some African American groups have identified risk signals but were underpowered, so this larger, community-focused effort builds on prior work while expanding to understudied populations.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Pericak-Vance, Margaret a. — University of Miami School of Medicine
- Study coordinator: Pericak-Vance, Margaret a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.