Building a data ecosystem for studying human gene expression and regulation
GTEx engagement with the CFDE-CC and other DCCs towards building a data ecosystem spanning the Common Fund projects
This study is all about digging deeper into how our genes work in different parts of the body to help us understand why some people get certain diseases, and it's designed to help patients by providing valuable insights into complex health issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Broad Institute, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-11093232 on NIH RePORTER |
What this research studies
This research focuses on enhancing the Genotype-Tissue Expression (GTEx) project, which provides a comprehensive resource for understanding human gene expression across various tissues. By collecting and analyzing extensive genetic and molecular data from deceased donors, the project aims to uncover how genetic variations influence disease susceptibility. Patients can benefit from this research as it seeks to improve our understanding of complex diseases through detailed genetic insights. The methodology includes advanced sequencing techniques and data analysis to create a rich database that can be utilized by the scientific community.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit include individuals with complex diseases or those interested in genetic research related to disease susceptibility.
Not a fit: Patients with conditions that are not influenced by genetic factors or those outside the age range of the study may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment options for complex diseases influenced by genetic factors.
How similar studies have performed: Previous research utilizing similar genetic data approaches has shown success in enhancing our understanding of gene regulation and disease mechanisms.
Where this research is happening
Cambridge, United States
- Broad Institute, INC. — Cambridge, United States (Active)
Researchers
- Principal investigator: Ardlie, Kristin — Broad Institute, INC.
- Study coordinator: Ardlie, Kristin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.