Bringing proven PrEP care to women at community clinics in the Southern U.S.

Implementation and Dissemination of Evidence-Based Interventions to Improve PrEP Care Continuum Outcomes Among Women in Community Health Clinics in the Southern U.S.

NIH-funded research University of Chicago · NIH-11131191

This project helps community health clinics in the Southern U.S. use proven methods to get more women started on and staying on HIV prevention (PrEP).

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11131191 on NIH RePORTER

What this research studies

This project will work with community health clinics across the Southern United States to adapt and scale up proven strategies that increase PrEP starts and continuation for women. Using the EPIS (Exploration, Preparation, Implementation, Sustainment) framework, the team will identify clinic needs, prepare staff, roll out interventions, and support long-term use. Clinics will track PrEP prescriptions and persistence through medical records and other measures, and the team will compare implementation approaches across clinic groups. The aim is to make it easier for women who could benefit from PrEP to access and remain on it.

Who could benefit from this research

Good fit: Women receiving care at participating community health clinics in the Southern U.S. who are at risk for HIV and eligible for PrEP are the ideal candidates.

Not a fit: People who do not attend the participating clinics, are not at risk for HIV, or who already use PrEP successfully may not directly benefit from this project.

Why it matters

Potential benefit: If successful, more women in the South could start and stay on PrEP, which may lower their risk of HIV infection.

How similar studies have performed: Earlier pilot work and smaller studies have shown that these implementation strategies can improve PrEP uptake and persistence in clinic settings, though wide-scale adoption in Southern community clinics is less tested.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.