Bringing HPV vaccination into adolescent HIV clinics in Zambia

Leveraging HIV infrastructure to implement cervical cancer prevention: A study to integrate HPV vaccination in adolescent HIV clinics in Zambia

NIH-funded research Washington University · NIH-11169975

This project will offer HPV vaccination and cervical cancer prevention as part of routine care for adolescent girls living with HIV in Zambia.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11169975 on NIH RePORTER

What this research studies

If you are an adolescent living with HIV in Zambia, you may be offered HPV vaccination and other cervical cancer prevention services during your regular HIV clinic visits. The team will work with clinic staff, the Ministry of Health, and community members to co-design how these services fit into routine care using the INSPIRE implementation approach. They will pilot the package in selected adolescent HIV clinics, train staff, improve supply chains, and collect feedback from patients and providers to refine the program. The project will monitor vaccine uptake and how well the new services are delivered in everyday clinic settings.

Who could benefit from this research

Good fit: Ideal candidates are adolescent girls living with HIV who attend participating adolescent HIV clinics in Zambia.

Not a fit: People who are not adolescent girls with HIV, those who do not attend participating clinics, or those already fully vaccinated are unlikely to receive direct benefit.

Why it matters

Potential benefit: If successful, this could substantially increase HPV vaccination and reduce future cervical cancer risk among adolescent girls living with HIV in Zambia.

How similar studies have performed: Similar integrated service and implementation approaches in low- and middle-income settings have improved uptake of health services, though integrating HPV vaccination into adolescent HIV clinics is relatively new and requires local adaptation.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusCancer BurdenCancer CauseCancer Etiology
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.