Bringing cervical cancer prevention to adolescent girls with HIV in Zambia

Leveraging HIV infrastructure to implement cervical cancer prevention in adolescent HIV clinics in Zambia

NIH-funded research Washington University · NIH-11400261

This project uses existing adolescent HIV clinics in Zambia to deliver proven cervical cancer prevention tools to girls living with HIV.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11400261 on NIH RePORTER

What this research studies

From your point of view, clinic staff will work with community members and health leaders to co-design ways to offer HPV vaccination, screening, and related care during routine visits. The team will use a proven implementation framework (INSPIRE) to tailor strategies that fit local resources, staffing, and supply systems. They will train clinic teams, strengthen supply chains, and track how well prevention services reach adolescents with HIV. The goal is to make prevention services part of regular adolescent HIV care so fewer girls develop cervical cancer in the future.

Who could benefit from this research

Good fit: Adolescent girls and young women living with HIV who attend adolescent HIV clinics in Zambia are the ideal candidates for this program.

Not a fit: People who are not adolescents, not living with HIV, or who live outside the clinic catchment areas in Zambia are unlikely to directly benefit from this project.

Why it matters

Potential benefit: If successful, this could increase access to vaccination and screening and reduce future cervical cancer cases and deaths among girls with HIV.

How similar studies have performed: INSPIRE-based interventions and clinic-focused implementation efforts have shown promise in low- and middle-income countries for improving cervical cancer prevention uptake, though adapting them specifically for adolescent HIV clinics is a newer approach.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusCancer BurdenCancer CauseCancer Etiology
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.