Bringing Alzheimer’s patient data together to find genetic clues
Alzheimer's Disease Sequencing Project Phenotype Harmonization Consortium
This project combines and standardizes clinical tests, brain scans, biomarkers, and genetic data to help researchers find better tests and treatments for people with Alzheimer’s and related dementias.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-11176283 on NIH RePORTER |
What this research studies
If you or a loved one have taken part in Alzheimer’s research, your cognitive tests, scans, fluid samples, or genetic results could be included in this effort. The team harmonizes and documents cognitive scores, neuroimaging, fluid and pathology measures, and sequencing data so different studies can be compared and combined. They build tools and clear documentation to streamline access for qualified researchers while coordinating with other large Alzheimer’s data efforts. The goal is to link detailed patient features with genetic information to speed discovery of disease mechanisms and therapeutic targets.
Who could benefit from this research
Good fit: People who have already participated in Alzheimer’s or related dementia research and provided clinical tests, imaging, fluid samples, or genetic data are the types most likely to be included in the harmonized datasets.
Not a fit: Individuals seeking immediate treatment or direct clinical care should not expect benefit, because the project focuses on organizing and sharing research data rather than delivering therapies.
Why it matters
Potential benefit: Could speed discovery of genetic causes and biomarkers that lead to better diagnostics and treatments for people with Alzheimer’s.
How similar studies have performed: Previous harmonization efforts (for example ADNI and other consortia) have helped researchers make discoveries, and this consortium extends those approaches to better connect genetic sequencing with rich clinical and biomarker data.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Hohman, Timothy J — Vanderbilt University Medical Center
- Study coordinator: Hohman, Timothy J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.