Brief anxiety treatment for people with early Alzheimer's or mild cognitive impairment and their caregivers

Randomized Clinical Trial of a Brief, Anxiety Intervention for Mild Cognitive Impairment/mild Alzheimer’s Disease and their Care Providers

NIH-funded research Florida State University · NIH-11259516

A short, focused therapy to help people with mild cognitive impairment or early Alzheimer's and their caregivers feel less anxious.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionFlorida State University NIH-funded
Lab location1 site (Tallahassee, United States)
Project IDNIH-11259516 on NIH RePORTER

What this research studies

If you join, you and your care partner would be randomly assigned to a brief anxiety program or usual care and followed over time. The sessions are short and built for people with memory problems, teaching ways to reduce sensitivity to bodily and emotional sensations that make anxiety worse. The program includes simple exercises and coping skills that do not rely heavily on memory, and caregivers are included so both of you can learn practical strategies. Researchers will track anxiety symptoms and daily functioning to see whether the approach helps patients and their care partners.

Who could benefit from this research

Good fit: Ideal candidates are people diagnosed with mild cognitive impairment or mild Alzheimer’s disease who have noticeable anxiety, along with their primary care partner.

Not a fit: People with moderate-to-severe dementia who cannot follow brief therapy steps or those without clinically significant anxiety are less likely to benefit.

Why it matters

Potential benefit: If successful, this could reduce anxiety for people with MCI or mild Alzheimer's and improve caregiver well‑being, possibly helping daily functioning.

How similar studies have performed: Therapies targeting anxiety sensitivity have shown promise in other groups, but brief interventions specifically tailored for people with MCI/early Alzheimer’s and their caregivers are relatively new and not yet widely proven.

Where this research is happening

Tallahassee, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's DiseaseAlzheimer's Disease and its related dementias
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.