Breaking up sitting to improve blood sugar in people at risk for type 2 diabetes
Admin Supplement to "Breaking up sedentary behaviors to improve glucose control in a population at risk for developing type 2 diabetes"
This compares short, frequent activity breaks during the day with one daily exercise session to find which approach helps blood sugar the most in adults with prediabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11186143 on NIH RePORTER |
What this research studies
If you join, you would be randomly assigned to either take many short activity breaks to interrupt sitting or to do one continuous daily bout of exercise with the same total activity time. The parent study started as a 4-week intervention and has been extended in some participants to 12 weeks with a 3-month follow-up. Staff collect blood sugar data (likely with glucose monitors and blood tests), activity patterns, and other health measures to understand how breaking up sitting affects glucose control. The supplement funds staff and data work to finish database cleaning and analysis so results can be shared sooner.
Who could benefit from this research
Good fit: Adults with prediabetes or at high risk for developing type 2 diabetes who can safely perform light-to-moderate physical activity and attend study visits are the ideal candidates.
Not a fit: People with established type 2 diabetes, those who cannot do physical activity, or those already very active may be less likely to benefit from this specific intervention.
Why it matters
Potential benefit: If successful, this could offer an easier, practical way for people with prediabetes to improve blood sugar and lower diabetes risk by changing daily sitting and activity patterns.
How similar studies have performed: Short-term laboratory studies have shown that interrupting prolonged sitting can improve post-meal glucose, but longer real-world randomized trials like this are less common.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Bergouignan, Audrey — University of Colorado Denver
- Study coordinator: Bergouignan, Audrey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.