Brain tumor seizures: a new approach to stopping seizures and potentially slowing tumor growth
Official title: Hong Proj-4
Funded at Dartmouth College · NIH-11406072 · Data updated 2026-11-12
This grant aims to study brain-tumor-related epilepsy and test new ways to reduce seizures for people with brain tumors.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project start | August 1, 2019 |
| Project end | June 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $262,413 |
| NIH project number | 5P20GM130454-08 |
| Project ID | NIH-11406072 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with brain tumors who experience seizures and have not achieved adequate seizure control.
✕Less likely to help
Patients without brain tumors or without seizures related to brain tumors are unlikely to benefit.
What this research studies
People with brain tumors often have seizures that are hard to control, and current medicines don’t help everyone. The project looks at how the brain tumor environment contributes to seizures and how stopping seizures might also slow tumor growth. Researchers plan to explore new ideas beyond standard drugs to disrupt the harmful brain-tumor interactions. If successful, this could lead to treatments that improve quality of life and long-term outcomes for patients with brain tumors.
Why it matters
Potential benefit: If successful, the work could reduce seizures and possibly slow tumor progression, improving daily function and quality of life for patients.
How similar studies have gone: Emerging research suggests that the tumor microenvironment and neuronal activity influence tumor behavior and seizure activity, with some approaches showing promise in preclinical work.
Where this research is happening
-
Dartmouth College
Hanover, United States Active
Researchers
- Principal investigator: Hong, Jennifer — Dartmouth College
- Study coordinator: Hong, Jennifer
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.