Brain scans and memory testing for older adults

Cognitive Assessment and Neuroimaging (CAN) Core E

['FUNDING_OTHER'] · UNIVERSITY OF ARIZONA · NIH-11184290

Collect brain imaging and memory tests from adults to find patterns linked to age-related thinking and memory changes.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF ARIZONA (nih funded)
Locations1 site (TUCSON, UNITED STATES)
Trial IDNIH-11184290 on ClinicalTrials.gov

What this research studies

If you join, you'll complete standardized memory and thinking tests online (in English or Spanish) and some participants will do in-person testing at one of four clinic sites. The study will also take brain MRIs and carotid ultrasound images from about 1,620 people using MRI protocols based on ADNI-3. Results will produce measurements of brain structure and white matter changes that researchers will link to individual differences in cognitive aging. The Core coordinates testing and imaging across sites (Tucson, Baltimore, Atlanta, Miami) to keep data consistent over time.

Who could benefit from this research

Good fit: Adults aged 21 and older, especially older adults experiencing or at risk for age-related memory or thinking changes, are the intended participants.

Not a fit: People under 21, those with conditions unrelated to age-related cognitive change, or individuals who cannot safely have an MRI (for example due to certain implants) may not benefit or be eligible.

Why it matters

Potential benefit: Could help doctors detect early brain changes tied to memory decline and improve diagnosis or monitoring of age-related cognitive problems.

How similar studies have performed: Large projects like ADNI have successfully used standardized cognitive testing and MRI to track aging and early dementia, so this approach builds on proven methods.

Where this research is happening

TUCSON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.