Brain network and computer modeling for understanding binge and heavy drinking
Network Analysis and Computational Modeling Core
They will use brain network analyses and computer models to find brain changes linked to binge and high-intensity drinking in people and animals.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project ID | NIH-11238451 on NIH RePORTER |
What this research studies
The center collects large, detailed brain and behavior data from people with different drinking patterns and from animal models using multiple techniques such as brain imaging and neural recordings. A dedicated core will apply network analysis and computational modeling to those multimodal datasets to identify circuit-level brain changes tied to binge and high-intensity drinking. The work intentionally combines human and rodent data to find common neural signatures that translate across species. The core also provides analysis tools and expertise to other teams in the center so findings are more integrated and reproducible.
Who could benefit from this research
Good fit: Ideal candidates are adults who engage in binge or high-intensity alcohol drinking and who can attend brain-imaging or behavioral testing at Indiana University in Indianapolis.
Not a fit: People without harmful alcohol use, those seeking immediate clinical treatment, or those unwilling or unable to travel to Indianapolis are unlikely to benefit directly from participation.
Why it matters
Potential benefit: If successful, this work could reveal brain circuit signals that predict or contribute to binge and heavy drinking and help guide new prevention or treatment strategies.
How similar studies have performed: Previous studies have linked brain imaging and network measures to alcohol use, but integrating large multimodal human and animal datasets into predictive computational models is a more recent and developing approach.
Where this research is happening
Indianapolis, United States
- Indiana University Indianapolis — Indianapolis, United States (Active)
Researchers
- Principal investigator: Lapish, Christopher Court — Indiana University Indianapolis
- Study coordinator: Lapish, Christopher Court
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.