Brain Health in Young Children with Type 1 Diabetes

Evaluating Neurocognitive Complications of Type 1 Diabetes (T1D) and Potential Risk and Protective Factors in Pre-Pubertal Children- New York University Clinical Center

['FUNDING_U01'] · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · NIH-11168864

This project looks at how Type 1 Diabetes affects brain development and thinking skills in young children.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorNEW YORK UNIVERSITY SCHOOL OF MEDICINE (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11168864 on ClinicalTrials.gov

What this research studies

Children with Type 1 Diabetes may experience mild thinking difficulties and altered brain development. This project aims to understand how factors like age at diagnosis, blood sugar control, and severe sugar events impact brain development. Researchers plan to involve up to 1,000 children before puberty, half of whom were recently diagnosed with Type 1 Diabetes. They will use MRI scans and cognitive tests over several years to observe changes in brain structure and thinking abilities. The goal is to identify who is most at risk and how to best support brain health in these children.

Who could benefit from this research

Good fit: Ideal candidates are pre-pubertal children, aged 0-11, with or without a recent diagnosis of Type 1 Diabetes.

Not a fit: Patients who are past puberty or do not fall within the specified age range would not be direct participants in this particular research.

Why it matters

Potential benefit: If successful, this could help us understand how to protect the brain health and thinking abilities of children with Type 1 Diabetes.

How similar studies have performed: While some risk factors have been identified, how they interact and who is most vulnerable remains poorly understood, indicating this approach aims to fill a significant knowledge gap.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.