Brain Health in Young Children with Type 1 Diabetes
Official title: Evaluating Neurocognitive Complications of Type 1 Diabetes (T1D) and Potential Risk and Protective Factors in Pre-Pubertal Children- New York University Clinical Center
Funded at New York University School of Medicine · NIH-11168864 · Data updated 2026-11-12
This project looks at how Type 1 Diabetes affects brain development and thinking skills in young children.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 15, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $600,343 |
| NIH project number | 5U01DK140791-02 |
| Project ID | NIH-11168864 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are pre-pubertal children, aged 0-11, with or without a recent diagnosis of Type 1 Diabetes.
✕Less likely to help
Patients who are past puberty or do not fall within the specified age range would not be direct participants in this particular research.
What this research studies
Children with Type 1 Diabetes may experience mild thinking difficulties and altered brain development. This project aims to understand how factors like age at diagnosis, blood sugar control, and severe sugar events impact brain development. Researchers plan to involve up to 1,000 children before puberty, half of whom were recently diagnosed with Type 1 Diabetes. They will use MRI scans and cognitive tests over several years to observe changes in brain structure and thinking abilities. The goal is to identify who is most at risk and how to best support brain health in these children.
Why it matters
Potential benefit: If successful, this could help us understand how to protect the brain health and thinking abilities of children with Type 1 Diabetes.
How similar studies have gone: While some risk factors have been identified, how they interact and who is most vulnerable remains poorly understood, indicating this approach aims to fill a significant knowledge gap.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Gallagher, Mary Patricia — New York University School of Medicine
- Study coordinator: Gallagher, Mary Patricia
Related research
Other NIH-funded projects on the same topics.
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Understanding brain changes in kids with new Type 1 diabetes
A multicenter study will follow young children with Type 1 diabetes and similar peers without diabetes to look for factors that influence brain development and thinking skills.
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Neurocognitive health in young kids with Type 1 diabetes and factors that help or hurt
A study following young children with Type 1 diabetes to understand how the condition affects thinking skills and behavior, and what factors might protect or worsen these effects.
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Understanding Brain Changes in Children with Type 1 Diabetes
This research aims to understand how Type 1 Diabetes affects brain development and thinking skills in children.
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Improving access to continuous glucose monitoring for children with type 1 diabetes.
This study is looking at how things like race and income affect whether kids with type 1 diabetes can use continuous glucose monitors (CGMs), and it aims to find ways to make sure all children have better access to this helpful technology for managing their diabetes.
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Investigating how type 1 diabetes affects brain development in young children
This study is looking at how type 1 diabetes affects the brain and thinking skills in young kids, and it’s inviting children with diabetes and those without to help us learn more by doing some fun brain tests and scans over a couple of years.
-
Understanding how Type 1 Diabetes affects brain development in children
This study is looking at how Type 1 Diabetes affects the thinking skills of young kids, exploring how things like high blood sugar can impact their brain development, so we can better understand and support children who might struggle with attention, learning, and memory.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.