NIH-funded research R01 grant

Brain health and digital memory tests for older Mandarin speakers

Official title: Neurological and digital correlates of cognition in Older Mandarin-speaking Adults

Funded at Rutgers Biomedical and Health Sciences · NIH-11456894 · Data updated 2026-11-12

This project creates Mandarin-based brain and digital tests to help detect early memory problems in older Mandarin-speaking adults.

More Cognition research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRutgers Biomedical and Health Sciences
NIH-funded
Lab location1 site (Newark, UNITED STATES)
Project startDecember 15, 2022
Project endNovember 30, 2027
Funding year2026
Award (this year)$718,929
NIH project number4R01AG079521-02
Project IDNIH-11456894 on NIH RePORTER

Who could benefit from this research

Could help

Older Mandarin-speaking adults who are concerned about memory changes, have mild cognitive symptoms, or are at risk for Alzheimer's disease would be ideal candidates.

Less likely to help

People who do not speak Mandarin or whose cognitive issues are caused by non-neurological problems are unlikely to benefit from these Mandarin-specific tests.

What this research studies

Many older Chinese Americans face delayed or missed diagnoses because most cognitive tests are simple translations and miss cultural or language differences. Researchers at Rutgers and Stanford have created new Mandarin neuropsychological tests adjusted for pronunciation, word frequency, and storytelling differences to match national Alzheimer assessment standards. The project combines these tailored tests with digital measures and neurological markers to spot mild cognitive impairment and early Alzheimer changes. The goal is to make diagnosis earlier and more accurate for Mandarin speakers so people can get care and join trials sooner.

Why it matters

Potential benefit: If successful, this work could lead to earlier and more accurate detection of memory problems for Mandarin speakers, enabling earlier treatment and trial access.

How similar studies have gone: Previous simple translations have often missed impairment, while culturally tailored cognitive tests have shown promise, and combining those tests with digital and neurological markers is a newer but promising approach.

Where this research is happening

  • Rutgers Biomedical and Health Sciences
    Newark, United States
    Active

Researchers

  • Principal investigator: Hu, William Tzu-Lung — Rutgers Biomedical and Health Sciences
  • Study coordinator: Hu, William Tzu-Lung

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.