Brain-controlled tablet communication

Intuitive, complete neural control of tablet computers for communication

['FUNDING_U01'] · BROWN UNIVERSITY · NIH-11159436

A fully implanted brain-computer interface that helps people with ALS or locked-in syndrome control a tablet and communicate without needing muscle movement.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorBROWN UNIVERSITY (nih funded)
Locations1 site (PROVIDENCE, UNITED STATES)
Trial IDNIH-11159436 on ClinicalTrials.gov

What this research studies

If you have severe speech and motor loss from ALS, brainstem stroke, or locked-in syndrome, this project will test an implanted brain device that turns your intended arm or hand movements into cursor control on a tablet. Surgeons implant sensors and researchers use decoding software to translate brain signals into taps, swipes, and typing in standard communication apps. The system is being designed to reduce daily caregiver setup, work in low light, and avoid tiring remaining physical abilities, with training sessions and regular follow-up for safety and calibration.

Who could benefit from this research

Good fit: Adults with severe speech and motor impairments (for example advanced ALS or locked-in syndrome from brainstem stroke) who are medically eligible for an implanted device and want to regain communication are the best candidates.

Not a fit: People who can speak or effectively use current AAC devices, those with medical reasons that prevent brain implant surgery, or those with severe cognitive impairment are unlikely to benefit.

Why it matters

Potential benefit: If successful, this could restore fast, intuitive communication for people who cannot speak or move and reduce dependence on caregivers.

How similar studies have performed: Prior BrainGate work has shown intracortical BCIs can allow a few participants to control a cursor and communicate, and this project builds on that by testing a fully implanted system.

Where this research is happening

PROVIDENCE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Amyotrophic Lateral Sclerosis Motor Neuron Disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.