NIH-funded research R01 grant

Brain-control interfaces that help people with paralysis reach and grasp more accurately

Official title: Examining Brain Areas to Identify Generalizable Neural Features to Improve Brain-Computer Interface Precision and Reliability

Funded at University of Kansas Medical Center · NIH-11431957 · Data updated 2026-11-12

A study to make brain-computer interfaces (BCIs) better at translating neural signals into smooth, reliable hand movements for people with paralysis, especially when reaching for new objects.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Kansas Medical Center
NIH-funded
Lab location1 site (Kansas City, United States)
Project startSeptember 3, 2026
Project endMay 31, 2031
Funding year2026
Award (this year)$580,517
NIH project number1R01NS150468-01
Project IDNIH-11431957 on NIH RePORTER

Who could benefit from this research

Could help

Individuals with paralysis or acquired brain injury who could use or benefit from BCI-assisted hand movements.

Less likely to help

Patients whose paralysis is not related to motor cortex dysfunction or who do not use BCIs may not directly benefit.

What this research studies

If you have a paralysis affecting hand movement, this project aims to improve how BCIs translate brain signals into grasping and reaching motions. Researchers will test how wrist position, hand shape, and new directions affect the ability to pick up unfamiliar objects. They will develop and compare decoding methods to make movement timing more natural and to use more neural information for better accuracy. Recordings will come from several brain areas involved in planning and guiding hand movements, using tasks that mimic real-world grasping. The work could lead to more intuitive control of robotic or stimulated limbs for daily activities.

Why it matters

Potential benefit: If successful, this work could make BCIs feel more natural and reliable for people with paralysis, helping them reach and grasp with less training.

How similar studies have gone: Past work shows that decoding neural signals can enable grasping, but improving generalization to novel movements remains challenging and is being actively explored.

Where this research is happening

  • University of Kansas Medical Center
    Kansas City, United States
    Active

Researchers

  • Principal investigator: Rouse, Adam G — University of Kansas Medical Center
  • Study coordinator: Rouse, Adam G

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.