Brain autopsy and pathology service for Alzheimer’s disease
Neuropathology Core
This program studies donated brains from older adults with and without memory problems to learn which brain changes are linked to Alzheimer’s disease.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Albert Einstein College of Medicine NIH-funded |
| Lab location | 1 site (Bronx, United States) |
| Project ID | NIH-11092275 on NIH RePORTER |
What this research studies
If I join the Einstein Aging Study and agree to brain donation, the Neuropathology Core will perform a timely autopsy and standardized tissue processing. The Montefiore neuropathology team harvests and prepares tissue and selected samples are sent to Mayo Clinic for further analysis. Diagnostic findings are entered into a linked database and written reports are shared with clinicians and family members. The team meets regularly to connect the autopsy results with each person’s clinical history to support research.
Who could benefit from this research
Good fit: Ideal candidates are older adults enrolled in the Einstein Aging Study who consent to post-mortem brain donation, including people with memory complaints and those with normal cognition.
Not a fit: People who are not enrolled in the Einstein Aging Study or who cannot or will not consent to brain donation will not be able to participate or receive direct benefit from this core.
Why it matters
Potential benefit: If successful, this work can improve understanding of the brain changes behind Alzheimer’s and help researchers develop better diagnostics and treatments.
How similar studies have performed: Brain banking and clinic-pathologic correlation studies have a long history of revealing Alzheimer’s-related brain changes and informing research and diagnosis.
Where this research is happening
Bronx, United States
- Albert Einstein College of Medicine — Bronx, United States (Active)
Researchers
- Principal investigator: Chin, Steven Suey-Ming — Albert Einstein College of Medicine
- Study coordinator: Chin, Steven Suey-Ming
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.