Brain Activity and Behavior in Lupus
Behavior and Electrophysiology Core
This core helps researchers understand how lupus affects brain activity and behavior in both mice and people.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Feinstein Institute for Medical Research NIH-funded |
| Lab location | 1 site (Manhasset, United States) |
| Project ID | NIH-11113400 on NIH RePORTER |
What this research studies
This research core provides specialized tools and support for studies looking into how lupus might affect the brain. We use advanced techniques to observe behavior and measure brain activity in both animal models and people living with lupus. Our goal is to understand how lupus antibodies might impact thinking, memory, and emotions. We also look at how these changes might show up in brainwave patterns during specific tasks. This work helps other scientists in the program project to make new discoveries about lupus.
Who could benefit from this research
Good fit: Individuals with Systemic Lupus Erythematosus (SLE) who are 21 years or older and willing to participate in brain activity (EEG) studies while performing spatial reasoning tasks might be ideal candidates.
Not a fit: Patients who do not have Systemic Lupus Erythematosus or are not interested in participating in brain activity measurements would not directly benefit from this specific aspect of the core's work.
Why it matters
Potential benefit: If successful, this core's work could help identify specific brain changes related to lupus, potentially leading to better ways to diagnose and treat cognitive and behavioral issues in patients.
How similar studies have performed: While the core itself is a support structure, the methods it employs, such as behavioral assays in animal models and EEG studies in humans, are established techniques in neuroscience and immunology research.
Where this research is happening
Manhasset, United States
- Feinstein Institute for Medical Research — Manhasset, United States (Active)
Researchers
- Principal investigator: Huerta, Patricio T — Feinstein Institute for Medical Research
- Study coordinator: Huerta, Patricio T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.