NIH-funded research NIH-funded research

Botswana‑Harvard HIV Clinical Trials Partnership

Official title: Botswana-Harvard T.H. Chan School of Public Health AIDS Initiative Partnership CTU

Funded at The Botswana Harvard Health Partnership · NIH-11412843 · Data updated 2026-11-12

This program runs clinical trials in Botswana to test new HIV treatments, prevention methods, and tuberculosis care for adults, children, and pregnant women.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionThe Botswana Harvard Health Partnership
NIH-funded
Lab location1 site (Gaborone, Botswana)
Project startFebruary 1, 2007
Project endNovember 30, 2027
Funding year2026
Award (this year)$2,118,250
NIH project number7UM1AI069456-20
Project IDNIH-11412843 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are adults and children living with HIV in Botswana, including pregnant women, and people being treated for or at risk of tuberculosis.

Less likely to help

People without HIV, those who live far from the trial sites, or those who do not meet specific health or age criteria would likely not be eligible or directly benefit.

What this research studies

If you live in or near Gaborone or Molepolole, this partnership offers trials that test HIV medicines and prevention tools for adults, children, and pregnant women. The Clinical Trials Unit works with three international research networks to run studies on durable HIV treatments, strategies to reduce or stop daily antiretroviral therapy, and better care for HIV‑related infections like tuberculosis. Trials take place at clinics in both an urban center and a large village so people from different communities can join. Eligible participants receive care from experienced teams, regular monitoring, and may be asked to provide blood or other samples during follow‑up.

Why it matters

Potential benefit: If successful, the work could bring safer, longer‑lasting HIV treatments, strategies to reduce or stop daily antiretroviral therapy, and improved prevention and treatment for tuberculosis and related infections.

How similar studies have gone: Previous HIV and TB clinical trials have produced many effective treatments and prevention tools, though approaches aiming for ART‑free remission remain experimental.

Where this research is happening

  • The Botswana Harvard Health Partnership
    Gaborone, Botswana
    Active

Researchers

  • Principal investigator: Makhema, Joseph Moeketsi — The Botswana Harvard Health Partnership
  • Study coordinator: Makhema, Joseph Moeketsi

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.