NIH-funded research Sbir 2 grant

BoostPrime: a digital tool to curb cravings in opioid use disorder

Official title: BoostPrime, A Novel Digital Therapeutic for Craving Mitigation in OUD

Funded at Nxtech INC · NIH-11300988 · Data updated 2026-11-12

A smartphone app called BoostPrime helps people with opioid use disorder manage cravings and strengthen moment-to-moment self-control.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionNxtech INC
NIH-funded
Lab location1 site (Houston, UNITED STATES)
Project startApril 15, 2023
Project endAugust 31, 2027
Funding year2026
Award (this year)$1,037,003
NIH project number5R44DA058531-03
Project IDNIH-11300988 on NIH RePORTER

Who could benefit from this research

Could help

Adults with opioid use disorder who are receiving MOUD and are open to digital cognitive training enhancements.

Less likely to help

Individuals not using MOUD or those without access to smartphones may not benefit.

What this research studies

This project will refine a smartphone-based software intervention that uses cognitive training exercises to reduce craving and support MOUD (medication for opioid use disorder) treatment. It plans to test adaptive, utilization-enhancing features and work with the FDA to plan regulated development. The team will conduct large-scale human testing of different platform variants to identify the best strategy for real-world use. If successful, BoostPrime could become a standard adjunct to MOUD to improve adherence and outcomes.

Why it matters

Potential benefit: If successful, BoostPrime could help people with OUD feel less craving and maintain treatment, potentially reducing relapse.

How similar studies have gone: Prior research suggests cognitive training can help with behavior change and craving management, and this platform has shown preliminary symptomatic benefits in high-utilizer groups.

Where this research is happening

  • Nxtech INC
    Houston, United States
    Active

Researchers

  • Principal investigator: Patel, Salil — Nxtech INC
  • Study coordinator: Patel, Salil

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.