Boosting spinal cord signals to improve balance and walking in older adults

Upregulating spinal circuits to enhance balance and walking and to increase spinal excitability in older adults

NIH-funded research University of Florida · NIH-11174490

A gentle, non-invasive spinal stimulation used with balance exercises aims to help people 65 and older walk and keep their balance better.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Florida NIH-funded
Lab location1 site (Gainesville, United States)
Project IDNIH-11174490 on NIH RePORTER

What this research studies

You would come to clinic for several sessions of dynamic balance training while a painless transcutaneous spinal direct current stimulation (tsDCS) is applied through pads on the skin over your lower spine. About 30 people aged 65 and older will take part in this multi-session trial, and the team will compare real stimulation with sham to see any differences. The researchers will measure walking, balance, everyday function, and spinal cord excitability before and after the training. The plan is to learn whether adding spinal stimulation helps older adults learn and keep balance skills better than training alone.

Who could benefit from this research

Good fit: Ideal candidates are ambulatory adults aged 65 or older who have mild-to-moderate balance or walking difficulties and can attend multiple in-person clinic sessions.

Not a fit: People with major neurological disease, implanted electrical devices (like pacemakers), active skin problems over the spine, or those unable to participate in repeated training sessions may not be eligible or benefit.

Why it matters

Potential benefit: If successful, this approach could improve walking and balance for older adults and reduce fall risk during everyday activities.

How similar studies have performed: Early pilot studies show spinal stimulation can change spinal excitability and motor function, but multi-session tsDCS combined with balance training in older adults is largely new and not yet proven at scale.

Where this research is happening

Gainesville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.