Boosting participation of African and Hispanic communities in Alzheimer's genetics
Recruitment and Retention for Alzheimer's Disease Diversity Genetic Cohorts in the ADSP (READD-ADSP)
This project invites people of African and Hispanic backgrounds to share health information and DNA so researchers can learn why Alzheimer's affects different communities.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Miami School of Medicine NIH-funded |
| Lab location | 1 site (Coral Gables, United States) |
| Project ID | NIH-11380169 on NIH RePORTER |
What this research studies
You may be asked to provide a saliva or blood sample, basic health and family history information, and permission for genetic testing and secure data sharing. The team will use community-sensitive recruitment and retention approaches to enroll around 13,000 people from diverse African and Hispanic ancestries. Collected samples will be genotyped and combined into a large, shared genomics resource to find genetic differences that influence Alzheimer's risk. Results will be used by researchers to improve understanding of disease biology across populations and guide future prevention or treatment efforts.
Who could benefit from this research
Good fit: Ideal participants are adults of African, African American, African Caribbean, or Hispanic/Latino ancestry who are willing to provide a DNA sample and basic health information, whether or not they have dementia symptoms.
Not a fit: People who are not of African or Hispanic genetic ancestry or who do not want to provide genetic samples are unlikely to get direct benefits from this project.
Why it matters
Potential benefit: If successful, this work could lead to more accurate genetic risk information and more inclusive approaches to prevention and treatment for people from African and Hispanic backgrounds.
How similar studies have performed: Smaller prior genetic studies in European and some African American groups have identified important risk genes but were underpowered, so this larger, diverse effort builds on promising but limited earlier findings.
Where this research is happening
Coral Gables, United States
- University of Miami School of Medicine — Coral Gables, United States (Active)
Researchers
- Principal investigator: Pericak-Vance, Margaret a. — University of Miami School of Medicine
- Study coordinator: Pericak-Vance, Margaret a.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.