Blood tests for Alzheimer's after brain injury
Blood-based AD biomarkers profile in CAPCOG-TBI study
This project looks at how blood markers for Alzheimer's disease change in people who have experienced a traumatic brain injury.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-11229668 on NIH RePORTER |
What this research studies
We know that a traumatic brain injury (TBI) can increase the risk of developing Alzheimer's disease or similar dementias. This project aims to understand how TBI might lead to these conditions by looking at specific markers in the blood. Researchers will use advanced blood tests, including those for Alzheimer's-related proteins and signs of brain injury or inflammation. This work builds on an existing study, CAPCOG-TBI, which follows people with TBI over time to see how their brain health changes.
Who could benefit from this research
Good fit: This project is interested in individuals who have experienced a traumatic brain injury.
Not a fit: Patients without a history of traumatic brain injury or concerns about Alzheimer's disease may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could help us better understand the link between brain injury and Alzheimer's, potentially leading to earlier diagnosis or new ways to prevent or treat the disease.
How similar studies have performed: Recent advances in blood tests for Alzheimer's disease and other brain injury markers show promise, and this project builds on that growing knowledge.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Ding, Kan — Ut Southwestern Medical Center
- Study coordinator: Ding, Kan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.